Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Avianca

The cheapest airline(s) flying from Medellin to Santiago is Avianca.

  • Avianca Avianca
  • JetSmart JetSmart
  • LATAM Airlines Group SA LATAM Airlines Group SA
  • Copa Airlines Copa Airlines
Cheapest Month September

Travel Period: April 2025 - March 2026

The cheapest month(s) to fly from Medellin to Santiago is September.

  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
  • Feb 2026
  • Mar 2026
Cheapest Day of the Week Monday

The cheapest day(s) of the week to fly from Medellin to Santiago is Monday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sun, 2 Mar, 2025

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  • Availability
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  • 17:50 MDE
    01:40 SCL
    5Hrs, 50m Direct
  • MDEMedellin Jose Maria Cordova Intl Airport 17:50 - SCL 01:40 5h 50m Direct
  • MDEMedellin Jose Maria Cordova Intl Airport 17:50
  • SCLSantiago Arturo Merino Benitez Airport 01:40
  • 5h 50m
  • Direct
  • Avianca (AV 123)Airbus A320 Neo
  • Avianca (AV 123)
    • M
    • -
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    • -
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  • Airbus A320 Neo
  • 19:15 MDE
    05:10 SCL
    7Hrs, 55m 1 Stop (BOG)
  • MDEMedellin Jose Maria Cordova Intl Airport 19:15 - SCL 05:10 7h 55m 1 Stop (BOG) Bogota
  • MDEMedellin Jose Maria Cordova Intl Airport 19:15
    BOGBogota Airport 21:30
  • BOGBogota Airport 20:12
    SCLSantiago Arturo Merino Benitez Airport 05:10
  • 7h 55m (1h 18m)
  • 1 Stop BOG · Bogota 1h 18m
  • Avianca (AV 9553)Airbus
    Avianca (AV 97)Boeing 787 8
  • Avianca (AV 9553)
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  • 10:14 MDE
    20:41 SCL
    8Hrs, 27m 1 Stop (LIM)
  • MDEMedellin Jose Maria Cordova Intl Airport 10:14 - SCL 20:41 8h 27m 1 Stop (LIM) Lima
  • MDEMedellin Jose Maria Cordova Intl Airport 10:14
    LIMLima Airport 15:10
  • LIMLima Airport 13:15
    SCLSantiago Arturo Merino Benitez Airport 20:41
  • 8h 27m (1h 55m)
  • 1 Stop LIM · Lima 1h 55m
  • JetSmart (JA 7755)Airbus
    JetSmart (JA 7733)Airbus
  • JetSmart (JA 7755)
    • -
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    • -
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  • 17:54 MDE
    05:11 SCL
    9Hrs, 17m 1 Stop (LIM)
  • MDEMedellin Jose Maria Cordova Intl Airport 17:54 - SCL 05:11 9h 17m 1 Stop (LIM) Lima
  • MDEMedellin Jose Maria Cordova Intl Airport 17:54
    LIMLima Airport 23:40
  • LIMLima Airport 20:55
    SCLSantiago Arturo Merino Benitez Airport 05:11
  • 9h 17m (2h 45m)
  • 1 Stop LIM · Lima 2h 45m
  • JetSmart (JA 7751)Airbus
    JetSmart (JA 7731)Airbus
  • JetSmart (JA 7751)
    • M
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What’s the fastest flight time from Medellin to Santiago?

The fastest flight time for direct flights from Medellin to Santiago is 5 hours 50 minutes. Check latest flight schedules & prices on Wego.

How far is Santiago from Medellin?

The flight distance between Medellin and Santiago is 4444km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 10:14. The last flight of the day departs at 19:15. See the full list of flight times on Wego.

How many airlines offer direct flights from Medellin to Santiago?

There are 1 airlines that offer direct flights from Medellin to Santiago. Find out the list of airlines on Wego.