Fare Guide
Estimated lowest fares found within 7 days
Cheapest Airline
The cheapest airline(s) flying from Chicago to Santa Ana is Alaska Airlines.
Cheapest Month
October
Travel Period: March 2025 - February 2026
The cheapest month(s) to fly from Chicago to Santa Ana is October.
Cheapest Day of the Week
Friday
The cheapest day(s) of the week to fly from Chicago to Santa Ana is Friday.
What’s the most popular airline flying from Chicago to Santa Ana?
The most popular airline flying from Chicago to Santa Ana is Frontier Airlines. Find the latest flight deals on Wego.
How far is Santa Ana from Chicago?
The flight distance between Chicago and Santa Ana is 2789km. Check all available flights on Wego.
Popular Airlines Flying From Chicago to Santa Ana
Popular Destinations From Santa Ana
Popular Destinations From Chicago
Popular Hotels in Santa Ana
- Best Western Plus Orange County Airport North
- Courtyard Santa Ana Orange County
- Holiday Inn SANTA ANA-ORANGE CO. ARPT
- DoubleTree by Hilton Santa Ana - Orange County Airport
- MainStay Suites Orange County John Wayne Airport
- Courtyard Costa Mesa South Coast Metro
- Holiday Inn Express & Suites SANTA ANA - ORANGE COUNTY
- Comfort Inn & Suites Orange County John Wayne Airport
- West Coast Inn Santa Ana
