Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Frontier Airlines

The cheapest airline(s) flying from Buffalo to Chicago is Frontier Airlines.

  • Frontier Airlines Frontier Airlines
  • JetBlue Airways JetBlue Airways
  • Delta Air Lines Delta Air Lines
  • American Airlines American Airlines
  • United Airlines United Airlines
  • Southwest Airlines Southwest Airlines
Cheapest Month October

Travel Period: October 2024 - September 2025

The cheapest month(s) to fly from Buffalo to Chicago is October.

  • Oct 2024
  • Nov 2024
  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Buffalo to Chicago is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Sep, 2024

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      • Availability
        • M
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        • S
      • 21:10 BUF
        21:45 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 21:10 - MDW 21:45 1h 35m Direct
      • BUFBuffalo Airport 21:10
      • MDWChicago Midway Airport 21:45
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 1085)Boeing 737 700
      • Southwest Airlines (WN 1085)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 06:05 BUF
        06:40 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 06:05 - MDW 06:40 1h 35m Direct
      • BUFBuffalo Airport 06:05
      • MDWChicago Midway Airport 06:40
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 2087)Boeing 737 800
      • Southwest Airlines (WN 2087)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 800
      • 07:00 BUF
        07:51 ORD
        1Hrs, 51m Direct
      • BUFBuffalo Airport 07:00 - ORD 07:51 1h 51m Direct
      • BUFBuffalo Airport 07:00
      • ORDChicago O'Hare International Airport 07:51
      • 1h 51m
      • Direct
      • United Airlines (UA 329)Boeing 737 800
      • United Airlines (UA 329)
        • M
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        • F
        • S
        • S
      • Boeing 737 800
      • 07:45 BUF
        08:33 ORD
        1Hrs, 48m Direct
      • BUFBuffalo Airport 07:45 - ORD 08:33 1h 48m Direct
      • BUFBuffalo Airport 07:45
      • ORDChicago O'Hare International Airport 08:33
      • 1h 48m
      • Direct
      • American Airlines (AA 2164)Boeing 737 800
      • American Airlines (AA 2164)
        • M
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        • T
        • F
        • S
        • S
      • Boeing 737 800
      • 08:05 BUF
        08:40 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 08:05 - MDW 08:40 1h 35m Direct
      • BUFBuffalo Airport 08:05
      • MDWChicago Midway Airport 08:40
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 2087)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 2087)
        • M
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        • T
        • F
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 10:40 BUF
        11:15 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 10:40 - MDW 11:15 1h 35m Direct
      • BUFBuffalo Airport 10:40
      • MDWChicago Midway Airport 11:15
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 977)Boeing 737 700
      • Southwest Airlines (WN 977)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 10:53 BUF
        11:52 ORD
        1Hrs, 59m Direct
      • BUFBuffalo Airport 10:53 - ORD 11:52 1h 59m Direct
      • BUFBuffalo Airport 10:53
      • ORDChicago O'Hare International Airport 11:52
      • 1h 59m
      • Direct
      • United Airlines (UA 3523)Embraer 175
      • United Airlines (UA 3523)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • Embraer 175
      • 10:53 BUF
        11:52 ORD
        1Hrs, 59m Direct
      • BUFBuffalo Airport 10:53 - ORD 11:52 1h 59m Direct
      • BUFBuffalo Airport 10:53
      • ORDChicago O'Hare International Airport 11:52
      • 1h 59m
      • Direct
      • United Airlines (UA 5695)Embraer 175
      • United Airlines (UA 5695)
        • -
        • -
        • -
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        • F
        • S
        • S
      • Embraer 175
      • 11:00 BUF
        11:35 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 11:00 - MDW 11:35 1h 35m Direct
      • BUFBuffalo Airport 11:00
      • MDWChicago Midway Airport 11:35
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 2035)Boeing 737 700
      • Southwest Airlines (WN 2035)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Boeing 737 700
      • 11:35 BUF
        12:24 ORD
        1Hrs, 49m Direct
      • BUFBuffalo Airport 11:35 - ORD 12:24 1h 49m Direct
      • BUFBuffalo Airport 11:35
      • ORDChicago O'Hare International Airport 12:24
      • 1h 49m
      • Direct
      • American Airlines (AA 2550)Boeing 737 800
      • American Airlines (AA 2550)
        • M
        • -
        • -
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        • F
        • -
        • S
      • Boeing 737 800
      • 13:55 BUF
        14:52 ORD
        1Hrs, 57m Direct
      • BUFBuffalo Airport 13:55 - ORD 14:52 1h 57m Direct
      • BUFBuffalo Airport 13:55
      • ORDChicago O'Hare International Airport 14:52
      • 1h 57m
      • Direct
      • United Airlines (UA 4381)Canadair Regional Jet 550
      • United Airlines (UA 4381)
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        • S
      • Canadair Regional Jet 550
      • 14:40 BUF
        15:15 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 14:40 - MDW 15:15 1h 35m Direct
      • BUFBuffalo Airport 14:40
      • MDWChicago Midway Airport 15:15
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 4441)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 4441)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 15:35 BUF
        16:10 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 15:35 - MDW 16:10 1h 35m Direct
      • BUFBuffalo Airport 15:35
      • MDWChicago Midway Airport 16:10
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 4441)Boeing 737 700
      • Southwest Airlines (WN 4441)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • Boeing 737 700
      • 16:05 BUF
        16:54 ORD
        1Hrs, 49m Direct
      • BUFBuffalo Airport 16:05 - ORD 16:54 1h 49m Direct
      • BUFBuffalo Airport 16:05
      • ORDChicago O'Hare International Airport 16:54
      • 1h 49m
      • Direct
      • American Airlines (AA 403)Boeing 737 800
      • American Airlines (AA 403)
        • -
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        • -
        • -
        • S
        • -
      • Boeing 737 800
      • 17:50 BUF
        18:25 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 17:50 - MDW 18:25 1h 35m Direct
      • BUFBuffalo Airport 17:50
      • MDWChicago Midway Airport 18:25
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 1297)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 1297)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 Max 8 Passenger
      • 17:59 BUF
        18:55 ORD
        1Hrs, 56m Direct
      • BUFBuffalo Airport 17:59 - ORD 18:55 1h 56m Direct
      • BUFBuffalo Airport 17:59
      • ORDChicago O'Hare International Airport 18:55
      • 1h 56m
      • Direct
      • United Airlines (UA 5500)Embraer 175
      • United Airlines (UA 5500)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Embraer 175
      • 18:02 BUF
        18:53 ORD
        1Hrs, 51m Direct
      • BUFBuffalo Airport 18:02 - ORD 18:53 1h 51m Direct
      • BUFBuffalo Airport 18:02
      • ORDChicago O'Hare International Airport 18:53
      • 1h 51m
      • Direct
      • United Airlines (UA 630)Boeing 737 Max 8 Passenger
      • United Airlines (UA 630)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 18:04 BUF
        18:55 ORD
        1Hrs, 51m Direct
      • BUFBuffalo Airport 18:04 - ORD 18:55 1h 51m Direct
      • BUFBuffalo Airport 18:04
      • ORDChicago O'Hare International Airport 18:55
      • 1h 51m
      • Direct
      • United Airlines (UA 630)Boeing 737 Max 8 Passenger
      • United Airlines (UA 630)
        • M
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        • -
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      • Boeing 737 Max 8 Passenger
      • 18:10 BUF
        18:45 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 18:10 - MDW 18:45 1h 35m Direct
      • BUFBuffalo Airport 18:10
      • MDWChicago Midway Airport 18:45
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 1297)Boeing 737 800
      • Southwest Airlines (WN 1297)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Boeing 737 800
      • 18:30 BUF
        19:19 ORD
        1Hrs, 49m Direct
      • BUFBuffalo Airport 18:30 - ORD 19:19 1h 49m Direct
      • BUFBuffalo Airport 18:30
      • ORDChicago O'Hare International Airport 19:19
      • 1h 49m
      • Direct
      • American Airlines (AA 403)Boeing 737 800
      • American Airlines (AA 403)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • Boeing 737 800
      • 18:40 BUF
        19:15 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 18:40 - MDW 19:15 1h 35m Direct
      • BUFBuffalo Airport 18:40
      • MDWChicago Midway Airport 19:15
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 3845)Boeing 737 700
      • Southwest Airlines (WN 3845)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 18:50 BUF
        19:25 MDW
        1Hrs, 35m Direct
      • BUFBuffalo Airport 18:50 - MDW 19:25 1h 35m Direct
      • BUFBuffalo Airport 18:50
      • MDWChicago Midway Airport 19:25
      • 1h 35m
      • Direct
      • Southwest Airlines (WN 3845)Boeing 737 800
      • Southwest Airlines (WN 3845)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • Boeing 737 800
      • 06:00 BUF
        10:04 ORD
        5Hrs, 04m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - ORD 10:04 5h 04m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 08:30
      • EWRNewark Liberty International Airport 07:24
        ORDChicago O'Hare International Airport 10:04
      • 5h 04m (1h 06m)
      • 1 Stop EWR · New York City 1h 06m
      • United Airlines (UA 1598)Boeing 737 700
        United Airlines (UA 1515)Boeing 737 Max 9 Passenger
      • United Airlines (UA 1598)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:15 BUF
        09:11 ORD
        3Hrs, 56m 1 Stop (DTW)
      • BUFBuffalo Airport 06:15 - ORD 09:11 3h 56m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 06:15
        DTWDetroit Wayne County 08:45
      • DTWDetroit Wayne County 07:25
        ORDChicago O'Hare International Airport 09:11
      • 3h 56m (1h 20m)
      • 1 Stop DTW · Detroit 1h 20m
      • Delta Air Lines (DL 2285)Airbus
        Delta Air Lines (DL 1654)Boeing 717
      • Delta Air Lines (DL 2285)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 06:15 BUF
        09:36 ORD
        4Hrs, 21m 1 Stop (IAD)
      • BUFBuffalo Airport 06:15 - ORD 09:36 4h 21m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 06:15
        IADWashington Dulles International Airport 08:25
      • IADWashington Dulles International Airport 07:32
        ORDChicago O'Hare International Airport 09:36
      • 4h 21m (53m)
      • 1 Stop IAD · Washington 53m
      • United Airlines (UA 6238)Embraer 175
        United Airlines (UA 1523)Boeing 737 900
      • United Airlines (UA 6238)
        • M
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        • T
        • F
        • S
        • S
      • 06:15 BUF
        08:52 MDW
        3Hrs, 37m 1 Stop (DTW)
      • BUFBuffalo Airport 06:15 - MDW 08:52 3h 37m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 06:15
        DTWDetroit Wayne County 08:35
      • DTWDetroit Wayne County 07:25
        MDWChicago Midway Airport 08:52
      • 3h 37m (1h 10m)
      • 1 Stop DTW · Detroit 1h 10m
      • Delta Air Lines (DL 2285)Airbus
        Delta Air Lines (DL 3858)Embraer 175
      • Delta Air Lines (DL 2285)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 09:00 BUF
        12:52 ORD
        4Hrs, 52m 1 Stop (DTW)
      • BUFBuffalo Airport 09:00 - ORD 12:52 4h 52m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 09:00
        DTWDetroit Wayne County 12:30
      • DTWDetroit Wayne County 10:16
        ORDChicago O'Hare International Airport 12:52
      • 4h 52m (2h 14m)
      • 1 Stop DTW · Detroit 2h 14m
      • Delta Air Lines (DL 4120)Canadair Regional
        Delta Air Lines (DL 1716)Boeing 717
      • Delta Air Lines (DL 4120)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 09:00 BUF
        12:28 MDW
        4Hrs, 28m 1 Stop (DTW)
      • BUFBuffalo Airport 09:00 - MDW 12:28 4h 28m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 09:00
        DTWDetroit Wayne County 12:15
      • DTWDetroit Wayne County 10:16
        MDWChicago Midway Airport 12:28
      • 4h 28m (1h 59m)
      • 1 Stop DTW · Detroit 1h 59m
      • Delta Air Lines (DL 5158)Canadair Regional
        Delta Air Lines (DL 3867)Embraer 175
      • Delta Air Lines (DL 5158)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 09:00 BUF
        12:28 MDW
        4Hrs, 28m 1 Stop (DTW)
      • BUFBuffalo Airport 09:00 - MDW 12:28 4h 28m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 09:00
        DTWDetroit Wayne County 12:15
      • DTWDetroit Wayne County 10:16
        MDWChicago Midway Airport 12:28
      • 4h 28m (1h 59m)
      • 1 Stop DTW · Detroit 1h 59m
      • Delta Air Lines (DL 4120)Canadair Regional
        Delta Air Lines (DL 3867)Embraer 175
      • Delta Air Lines (DL 4120)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 09:00 BUF
        12:52 ORD
        4Hrs, 52m 1 Stop (DTW)
      • BUFBuffalo Airport 09:00 - ORD 12:52 4h 52m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 09:00
        DTWDetroit Wayne County 12:30
      • DTWDetroit Wayne County 10:16
        ORDChicago O'Hare International Airport 12:52
      • 4h 52m (2h 14m)
      • 1 Stop DTW · Detroit 2h 14m
      • Delta Air Lines (DL 5158)Canadair Regional
        Delta Air Lines (DL 1716)Boeing 717
      • Delta Air Lines (DL 5158)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 09:45 BUF
        13:20 MDW
        4Hrs, 35m 1 Stop (BWI)
      • BUFBuffalo Airport 09:45 - MDW 13:20 4h 35m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 09:45
        BWIBaltimore Washington International Airport 12:20
      • BWIBaltimore Washington International Airport 10:55
        MDWChicago Midway Airport 13:20
      • 4h 35m (1h 25m)
      • 1 Stop BWI · Baltimore 1h 25m
      • Southwest Airlines (WN 694)Boeing 737 700
        Southwest Airlines (WN 3716)Boeing 737 700
      • Southwest Airlines (WN 694)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 10:08 BUF
        13:51 ORD
        4Hrs, 43m 1 Stop (LGA)
      • BUFBuffalo Airport 10:08 - ORD 13:51 4h 43m 1 Stop (LGA) New York City
      • BUFBuffalo Airport 10:08
        LGANew York La Guardia Airport 12:13
      • LGANew York La Guardia Airport 11:31
        ORDChicago O'Hare International Airport 13:51
      • 4h 43m (42m)
      • 1 Stop LGA · New York City 42m
      • American Airlines (AA 4738)Embraer Emb 175
        American Airlines (AA 386)Boeing 737 800
      • American Airlines (AA 4738)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 10:23 BUF
        14:06 ORD
        4Hrs, 43m 1 Stop (CLT)
      • BUFBuffalo Airport 10:23 - ORD 14:06 4h 43m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 10:23
        CLTCharlotte Airport 13:00
      • CLTCharlotte Airport 12:19
        ORDChicago O'Hare International Airport 14:06
      • 4h 43m (41m)
      • 1 Stop CLT · Charlotte 41m
      • American Airlines (AA 1203)Airbus
        American Airlines (AA 1650)Boeing 737 800
      • American Airlines (AA 1203)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • 10:23 BUF
        14:06 ORD
        4Hrs, 43m 1 Stop (CLT)
      • BUFBuffalo Airport 10:23 - ORD 14:06 4h 43m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 10:23
        CLTCharlotte Airport 13:00
      • CLTCharlotte Airport 12:19
        ORDChicago O'Hare International Airport 14:06
      • 4h 43m (41m)
      • 1 Stop CLT · Charlotte 41m
      • American Airlines (AA 1203)Airbus
        American Airlines (AA 1650)Boeing 737 800
      • American Airlines (AA 1203)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 10:25 BUF
        13:55 ORD
        4Hrs, 30m 1 Stop (IAD)
      • BUFBuffalo Airport 10:25 - ORD 13:55 4h 30m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 10:25
        IADWashington Dulles International Airport 12:48
      • IADWashington Dulles International Airport 11:43
        ORDChicago O'Hare International Airport 13:55
      • 4h 30m (1h 05m)
      • 1 Stop IAD · Washington 1h 05m
      • United Airlines (UA 6072)Embraer 175
        United Airlines (UA 1562)Airbus
      • United Airlines (UA 6072)
        • M
        • -
        • W
        • T
        • F
        • S
        • S
      • 10:40 BUF
        14:25 ORD
        4Hrs, 45m 1 Stop (BWI)
      • BUFBuffalo Airport 10:40 - ORD 14:25 4h 45m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 10:40
        BWIBaltimore Washington International Airport 13:10
      • BWIBaltimore Washington International Airport 11:50
        ORDChicago O'Hare International Airport 14:25
      • 4h 45m (1h 20m)
      • 1 Stop BWI · Baltimore 1h 20m
      • Southwest Airlines (WN 3245)Boeing 737 700
        Southwest Airlines (WN 4496)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3245)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 10:50 BUF
        14:15 ORD
        4Hrs, 25m 1 Stop (BWI)
      • BUFBuffalo Airport 10:50 - ORD 14:15 4h 25m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 10:50
        BWIBaltimore Washington International Airport 13:00
      • BWIBaltimore Washington International Airport 12:00
        ORDChicago O'Hare International Airport 14:15
      • 4h 25m (1h)
      • 1 Stop BWI · Baltimore 1h
      • Southwest Airlines (WN 1912)Boeing 737 700
        Southwest Airlines (WN 2024)Boeing 737 700
      • Southwest Airlines (WN 1912)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 10:50 BUF
        14:30 MDW
        4Hrs, 40m 1 Stop (BWI)
      • BUFBuffalo Airport 10:50 - MDW 14:30 4h 40m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 10:50
        BWIBaltimore Washington International Airport 13:30
      • BWIBaltimore Washington International Airport 12:00
        MDWChicago Midway Airport 14:30
      • 4h 40m (1h 30m)
      • 1 Stop BWI · Baltimore 1h 30m
      • Southwest Airlines (WN 3396)Boeing 737 800
        Southwest Airlines (WN 3727)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3396)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • 10:50 BUF
        14:00 ORD
        4Hrs, 10m 1 Stop (BWI)
      • BUFBuffalo Airport 10:50 - ORD 14:00 4h 10m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 10:50
        BWIBaltimore Washington International Airport 12:45
      • BWIBaltimore Washington International Airport 12:00
        ORDChicago O'Hare International Airport 14:00
      • 4h 10m (45m)
      • 1 Stop BWI · Baltimore 45m
      • Southwest Airlines (WN 3396)Boeing 737 800
        Southwest Airlines (WN 4496)Boeing 737 800
      • Southwest Airlines (WN 3396)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • 11:35 BUF
        15:35 ORD
        5Hrs, 00m 1 Stop (PHL)
      • BUFBuffalo Airport 11:35 - ORD 15:35 5h 1 Stop (PHL) Philadelphia
      • BUFBuffalo Airport 11:35
        PHLPhiladelphia International Airport 14:12
      • PHLPhiladelphia International Airport 12:54
        ORDChicago O'Hare International Airport 15:35
      • 5h (1h 18m)
      • 1 Stop PHL · Philadelphia 1h 18m
      • American Airlines (AA 5028)Canadair Regional
        American Airlines (AA 1739)Airbus
      • American Airlines (AA 5028)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 11:46 BUF
        16:01 ORD
        5Hrs, 15m 1 Stop (CLT)
      • BUFBuffalo Airport 11:46 - ORD 16:01 5h 15m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 11:46
        CLTCharlotte Airport 14:48
      • CLTCharlotte Airport 13:42
        ORDChicago O'Hare International Airport 16:01
      • 5h 15m (1h 06m)
      • 1 Stop CLT · Charlotte 1h 06m
      • American Airlines (AA 1203)Airbus
        American Airlines (AA 2576)Airbus
      • American Airlines (AA 1203)
        • -
        • T
        • W
        • -
        • -
        • S
        • -
      • 11:55 BUF
        15:46 ORD
        4Hrs, 51m 1 Stop (DCA)
      • BUFBuffalo Airport 11:55 - ORD 15:46 4h 51m 1 Stop (DCA) Washington
      • BUFBuffalo Airport 11:55
        DCAWashington Ronald Reagan National Airport 14:34
      • DCAWashington Ronald Reagan National Airport 13:14
        ORDChicago O'Hare International Airport 15:46
      • 4h 51m (1h 20m)
      • 1 Stop DCA · Washington 1h 20m
      • American Airlines (AA 5093)Crj 700 Canadair Regional
        American Airlines (AA 1187)Airbus
      • American Airlines (AA 5093)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 13:11 BUF
        17:03 ORD
        4Hrs, 52m 1 Stop (PHL)
      • BUFBuffalo Airport 13:11 - ORD 17:03 4h 52m 1 Stop (PHL) Philadelphia
      • BUFBuffalo Airport 13:11
        PHLPhiladelphia International Airport 15:40
      • PHLPhiladelphia International Airport 14:34
        ORDChicago O'Hare International Airport 17:03
      • 4h 52m (1h 06m)
      • 1 Stop PHL · Philadelphia 1h 06m
      • American Airlines (AA 5868)Er4 Embraer Rj145 Amazon
        American Airlines (AA 1969)Boeing 737 800
      • American Airlines (AA 5868)
        • M
        • T
        • -
        • T
        • F
        • S
        • S
      • 13:40 BUF
        17:44 ORD
        5Hrs, 04m 1 Stop (DCA)
      • BUFBuffalo Airport 13:40 - ORD 17:44 5h 04m 1 Stop (DCA) Washington
      • BUFBuffalo Airport 13:40
        DCAWashington Ronald Reagan National Airport 16:31
      • DCAWashington Ronald Reagan National Airport 14:59
        ORDChicago O'Hare International Airport 17:44
      • 5h 04m (1h 32m)
      • 1 Stop DCA · Washington 1h 32m
      • American Airlines (AA 5640)Crj 700 Canadair Regional
        American Airlines (AA 1263)Boeing 737 800
      • American Airlines (AA 5640)
        • M
        • T
        • W
        • T
        • F
        • -
        • -
      • 13:41 BUF
        17:44 ORD
        5Hrs, 03m 1 Stop (DCA)
      • BUFBuffalo Airport 13:41 - ORD 17:44 5h 03m 1 Stop (DCA) Washington
      • BUFBuffalo Airport 13:41
        DCAWashington Ronald Reagan National Airport 16:31
      • DCAWashington Ronald Reagan National Airport 15:00
        ORDChicago O'Hare International Airport 17:44
      • 5h 03m (1h 31m)
      • 1 Stop DCA · Washington 1h 31m
      • American Airlines (AA 5640)Crj 700 Canadair Regional
        American Airlines (AA 1263)Boeing 737 800
      • American Airlines (AA 5640)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 13:43 BUF
        17:49 ORD
        5Hrs, 06m 1 Stop (CLT)
      • BUFBuffalo Airport 13:43 - ORD 17:49 5h 06m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 13:43
        CLTCharlotte Airport 16:35
      • CLTCharlotte Airport 15:39
        ORDChicago O'Hare International Airport 17:49
      • 5h 06m (56m)
      • 1 Stop CLT · Charlotte 56m
      • American Airlines (AA 2975)Airbus
        American Airlines (AA 536)Airbus
      • American Airlines (AA 2975)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 14:40 BUF
        18:50 MDW
        5Hrs, 10m 1 Stop (BWI)
      • BUFBuffalo Airport 14:40 - MDW 18:50 5h 10m 1 Stop (BWI) Baltimore
      • BUFBuffalo Airport 14:40
        BWIBaltimore Washington International Airport 17:50
      • BWIBaltimore Washington International Airport 15:50
        MDWChicago Midway Airport 18:50
      • 5h 10m (2h)
      • 1 Stop BWI · Baltimore 2h
      • Southwest Airlines (WN 1199)Boeing 737 800
        Southwest Airlines (WN 528)Boeing 737 700
      • Southwest Airlines (WN 1199)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • 15:00 BUF
        19:05 ORD
        5Hrs, 05m 1 Stop (IAD)
      • BUFBuffalo Airport 15:00 - ORD 19:05 5h 05m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 15:00
        IADWashington Dulles International Airport 17:44
      • IADWashington Dulles International Airport 16:17
        ORDChicago O'Hare International Airport 19:05
      • 5h 05m (1h 27m)
      • 1 Stop IAD · Washington 1h 27m
      • United Airlines (UA 4291)Embraer
        United Airlines (UA 2497)Boeing 757 200 Series
      • United Airlines (UA 4291)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 15:00 BUF
        18:55 ORD
        4Hrs, 55m 1 Stop (IAD)
      • BUFBuffalo Airport 15:00 - ORD 18:55 4h 55m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 15:00
        IADWashington Dulles International Airport 17:34
      • IADWashington Dulles International Airport 16:17
        ORDChicago O'Hare International Airport 18:55
      • 4h 55m (1h 17m)
      • 1 Stop IAD · Washington 1h 17m
      • United Airlines (UA 4291)Embraer
        United Airlines (UA 2497)Boeing 757 200 Series
      • United Airlines (UA 4291)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 17:33 BUF
        21:41 ORD
        5Hrs, 08m 1 Stop (CLT)
      • BUFBuffalo Airport 17:33 - ORD 21:41 5h 08m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 17:33
        CLTCharlotte Airport 20:29
      • CLTCharlotte Airport 19:29
        ORDChicago O'Hare International Airport 21:41
      • 5h 08m (1h)
      • 1 Stop CLT · Charlotte 1h
      • American Airlines (AA 2301)Airbus
        American Airlines (AA 1048)Boeing 737 800
      • American Airlines (AA 2301)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 17:35 BUF
        21:41 ORD
        5Hrs, 06m 1 Stop (CLT)
      • BUFBuffalo Airport 17:35 - ORD 21:41 5h 06m 1 Stop (CLT) Charlotte
      • BUFBuffalo Airport 17:35
        CLTCharlotte Airport 20:29
      • CLTCharlotte Airport 19:31
        ORDChicago O'Hare International Airport 21:41
      • 5h 06m (58m)
      • 1 Stop CLT · Charlotte 58m
      • American Airlines (AA 2301)Airbus
        American Airlines (AA 1048)Boeing 737 800
      • American Airlines (AA 2301)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 17:48 BUF
        21:01 ORD
        4Hrs, 13m 1 Stop (DTW)
      • BUFBuffalo Airport 17:48 - ORD 21:01 4h 13m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 17:48
        DTWDetroit Wayne County 20:40
      • DTWDetroit Wayne County 19:04
        ORDChicago O'Hare International Airport 21:01
      • 4h 13m (1h 36m)
      • 1 Stop DTW · Detroit 1h 36m
      • Delta Air Lines (DL 1292)Boeing 717
        Delta Air Lines (DL 1665)Boeing 717
      • Delta Air Lines (DL 1292)
        • M
        • T
        • W
        • -
        • F
        • -
        • S
      • 17:48 BUF
        21:01 ORD
        4Hrs, 13m 1 Stop (DTW)
      • BUFBuffalo Airport 17:48 - ORD 21:01 4h 13m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 17:48
        DTWDetroit Wayne County 20:40
      • DTWDetroit Wayne County 19:07
        ORDChicago O'Hare International Airport 21:01
      • 4h 13m (1h 33m)
      • 1 Stop DTW · Detroit 1h 33m
      • Delta Air Lines (DL 3663)Canadair Regional
        Delta Air Lines (DL 1665)Boeing 717
      • Delta Air Lines (DL 3663)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 17:53 BUF
        21:01 ORD
        4Hrs, 08m 1 Stop (DTW)
      • BUFBuffalo Airport 17:53 - ORD 21:01 4h 08m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 17:53
        DTWDetroit Wayne County 20:40
      • DTWDetroit Wayne County 19:09
        ORDChicago O'Hare International Airport 21:01
      • 4h 08m (1h 31m)
      • 1 Stop DTW · Detroit 1h 31m
      • Delta Air Lines (DL 1292)Airbus
        Delta Air Lines (DL 1665)Boeing 717
      • Delta Air Lines (DL 1292)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 19:48 BUF
        23:14 ORD
        4Hrs, 26m 1 Stop (IAD)
      • BUFBuffalo Airport 19:48 - ORD 23:14 4h 26m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 19:48
        IADWashington Dulles International Airport 22:10
      • IADWashington Dulles International Airport 21:07
        ORDChicago O'Hare International Airport 23:14
      • 4h 26m (1h 03m)
      • 1 Stop IAD · Washington 1h 03m
      • United Airlines (UA 4911)Embraer
        United Airlines (UA 1738)Airbus
      • United Airlines (UA 4911)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:48 BUF
        23:14 ORD
        4Hrs, 26m 1 Stop (IAD)
      • BUFBuffalo Airport 19:48 - ORD 23:14 4h 26m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 19:48
        IADWashington Dulles International Airport 22:10
      • IADWashington Dulles International Airport 21:06
        ORDChicago O'Hare International Airport 23:14
      • 4h 26m (1h 04m)
      • 1 Stop IAD · Washington 1h 04m
      • United Airlines (UA 6064)Embraer 175
        United Airlines (UA 1738)Airbus
      • United Airlines (UA 6064)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
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      What’s the fastest flight time from Buffalo to Chicago?

      The fastest flight time for direct flights from Buffalo to Chicago is 1 hour 35 minutes. Check latest flight schedules & prices on Wego.

      How far is Chicago from Buffalo?

      The flight distance between Buffalo and Chicago is 727km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 06:00. The last flight of the day departs at 21:10. See the full list of flight times on Wego.

      How many airlines offer direct flights from Buffalo to Chicago?

      There are 3 airlines that offer direct flights from Buffalo to Chicago. Find out the list of airlines on Wego.

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